Project may aid in treating obesity

Christopher Brower (biology) and graduate research assistant Yasar Kasu have been awarded $1,500 from the Texas Society for Microscopy for Kasu’s graduate proposal, “Developing High-throughput screen for Modulators of the Arginylation Dependent N-end Rule Pathway.” Brower and Kasu propose the development of a high throughput screen utilizing dual fluorescent reporters to identify small molecule modulators of ATE1 and the N‐end rule pathway. This project involves modern molecular biology techniques including extensive use of fluorescent confocal microscopy. Ultimately, this project may help in designing treatment strategies against obesity.